TROMBOSiTOZ
Tanım: Trombositoz; trombosit sayısının 450.000/mm3‘ün üzerinde olmasıdır. Myeloproliferatif hastalıkların hemen hepsinde trombositoz görülebilmekle birlikte en sık görülen hastalık esansiyel trombositozdur. Tromboz riski ile trombosit sayısı arasında net bir ilişki olmamakla birlikte, trombosit sayısı 1.500.000/mm3‘un üzerine çıktığında daha çok kanama riski artmaktadır.
Gerekçe: Myeloproliferatif hastalıklarda kanama ve tromboz varlığında, ciddi kontrol edilemeyen trombositozlarda kullanılabilir.
İşlem: Trombositaferez
Sıklığı: Günlük
İşlenen Volüm: 1,5-2 TKH
Replasman Sıvısı: SF
Uygulama sayı ve/veya süresi: Akut tromboemboli ve kanama durumunda hedef trombosit sayısının sitoreduktif tedavi etkisini gösterene kadar normal düzeylerde tutulmasıdır. Bilinen başka bir klinik öykü yoksa 600.000/mm3‘ün altına indirmek yeterlidir.
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